LOUISVILLE, Ky. (AP) 鈥 On a crisp, clear morning, a chestnut thoroughbred thundered down the dirt strip at Churchill Downs, his exercise rider leaning forward above the saddle. Other horse-and-rider pairs followed.

Dr. Will Farmer looked down from a viewing point, admiring the speed and agility of the 1,000-pound animals.

The whole world will have the chance to see here Saturday, when shines a global spotlight on equine athleticism. It鈥檚 the subject of a growing body of research that cites a constellation of characteristics: big hearts, immense lung capacity, robust musculoskeletal systems and long, thin legs 鈥 all of which helped horses survive in the wild.

鈥淚t goes back to the roots: They are an animal of prey,鈥 said Farmer, a veterinarian and equine medical director at Churchill Downs Inc. 鈥淭hat鈥檚 how they got away from being eaten.鈥

Horses honed skills such as running, jumping and pulling as humans bred and trained them for various purposes over millennia. And the 151st Derby 鈥 horse racing's most-watched event 鈥 will draw attention not only to the animals' skills, but also to concerns about their treatment and health. Advocates have long raised concerns about deaths and injuries 鈥 calls that were amplified two years ago, when at Churchill Downs.

There's no doubt that war, agriculture and societies have been transformed by the human-horse relationship.

鈥淗orses allowed us to circumvent our own biological limitations as a species,鈥 said Timothy Winegard, a historian at Colorado Mesa University and author of a recent book, 鈥淭he Horse.鈥 鈥淲e combined our brains with the horses鈥 size, strength, stamina and speed to form the most unstoppable animal coalition.鈥

What makes horses so powerful?

A horse鈥檚 heart and lungs are the source of its extraordinary power.

The heart averages 10 to 12 pounds (4.5-5.4 kg), or about 1% of the animal鈥檚 body weight, compared with half a percent for the typical human heart. that won the Triple Crown in 1973, was found after his death to have a heart weighing more than 20 pounds (9.1 kg).

Horse hearts are built for exertion. The average horse can go from a resting heart rate of about 34 beats per minute to 220 or 240 while racing 鈥 faster than a human heart during maximum exertion.

鈥淥ne thing that鈥檚 really unique about horses is that they have an incredible capacity to move blood around their bodies -- their heart rate can go really high and still be safe,鈥 said University of Connecticut researcher Sarah Reed, editor in chief of the journal Animal Frontiers.

They also have a lung capacity of 60 liters 鈥 10 times that of humans.

鈥淭hat massive lung field allows for oxygen to transfer from the air into their blood, which is vitally important for sustaining aerobic energy,鈥 Farmer said.

in the journal Science found that a genetic mutation enables horses to avoid negative side effects of super high energy production.

鈥淗orses are great athletes because they can deliver a lot of oxygen to their muscles 鈥 way more than an elite human can 鈥攁nd by elite human, I mean Olympic athlete,鈥 said Gianni Castiglione, the study's co-author. 鈥淭hey have a bigger tank of gas and they have a more efficient engine 鈥 and this mutation is contributing to both of those things.鈥

What is behind horses' speed and other skills?

Other aspects of a horse's biology enhance its abilities.

Horses store extra red blood cells in their spleens. These cells are released to carry even more oxygen around the body during intense exertion.

鈥淎drenaline when exercising causes the spleen to release extra red blood cells into circulation,鈥 veterinarian Hilary Clayton said. 鈥淲hat horses are doing is essentially 鈥榖lood doping鈥 themselves.鈥

Meanwhile, horses' brains allow them to process sensory information and react quickly. That鈥檚 despite having frontal lobes, parts of the brain used for thought and planning that are proportionally smaller than those in humans.

鈥淏rainwise, they鈥檙e designed with a real desire to play and run independent of any fear,鈥 said Dr. Scott Bailey, a veterinarian at Claiborne Farm in Paris, Kentucky, a thoroughbred breeding farm where Secretariat is buried. Horses are also able to focus intently, which 鈥渋s really important for an athlete.鈥

Bone structure and musculature also help. The ligaments and tendons in their hind legs act like springs, Farmer said, helping propel them forward. Like other large prey animals, he added, they have 鈥渓ong, thin legs that are meant to run.鈥

What about the risks for horses?

The adaptations that make horses faster also predispose them to injury, Reed said. Their skinny legs absorb the impact of each stride, she said, and over time the repetitive stress of racing and training can lead to deformation of tendons and ligaments.

In 2023, deaths occurred not only at Churchill Downs, but other major racing venues, affecting public perceptions of the sport and sparking changes. Reviews found no single cause for the deaths. But for 2024, Churchill Downs upgraded equipment used on its dirt surface and added an equine safety and integrity veterinarian.

In its , the Horseracing Integrity and Safety Authority noted the steps being taken to reduce injuries and fatalities 鈥 expanded veterinary protocols, pre-race inspections and uniform medication oversight. And, it said, the rate of deaths at authority-accredited tracks dropped in 2024, by 27%.

What makes a champion?

Experts say a healthy, safe environment brings out the best in a horse 鈥 but they still don't know what makes certain horses standouts at the race track.

鈥淭hat鈥檚 the million-dollar question,鈥 Bailey said. 鈥淓very thoroughbred owner is trying to match the genetics of the parents in order to make the horse with the greatest chance of winning.鈥

Breeding is only part of the equation, experts said; nurture, training and the horse-rider relationship also factor in. Each time a horse emerges seemingly out of nowhere to win the Kentucky Derby, Farmer is reminded of this.

鈥淵ou don鈥檛 have to be this star-studded bred horse that cost a million dollars at sale to come and win and be a great runner,鈥 he said, raising his voice slightly above the din of galloping hooves. 鈥淭here are a lot of great horses.鈥

___

Larson reported from Washington, D.C.

鈥斺赌

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute鈥檚 Science and Educational Media Group and the Robert Wood Johnson Foundation. The AP is solely responsible for all content.

The 好色tv Press. All rights reserved.