KYIV, Ukraine (AP) — Ukraine fired several American-supplied longer-range missiles into Russia, officials said Tuesday, marking the first time Kyiv used the weapons that way in 1,000 days of war.

The use of the , came as Russian President Vladimir Putin for using nuclear weapons, opening the door to a potential nuclear response by Moscow to even a conventional attack by any nation supported by a nuclear power. That could include Ukrainian attacks backed by the U.S.

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