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Homeland Security spokesperson Tricia McLaughlin later told Fox News that no ICE agents were injured.

“We believe he was shooting at law enforcement and detainees from an apartment building,� McLaughlin said. �Detainees were among the victims of the shooting."

Officers responded to a call to assist an officer on North Stemmons Freeway around 6:40 a.m. Wednesday and the preliminary investigation determined that a person opened fire at a government building from an adjacent building, Dallas police spokesperson Officer Jonathen E. Maner said in an email.

The Dallas Fire-Rescue Department was also dispatched after a call reporting a shooting at or near the immigration office, department spokesperson Jason L. Evans said in an email.

Parkland Hospital has received two patients from the shooting, hospital spokesperson April Foran said by telephone. She did not have any details about their conditions.

A third person died at the scene after the shooting, Maner said. The investigation is ongoing and a briefing was expected later in the day.

Dozens of emergency vehicles were seen along a highway near the facility.

The ICE facility is along Interstate 35 East, just southwest of Dallas Love Field, a large commercial airport serving the Dallas-Fort Worth metropolitan area, and just blocks from hotels catering to airport travelers.

Traffic cameras near the scene showed six lanes of a normally busy freeway empty, with cars and semitrailers ground to a halt on an interstate exit.

Homeland Security Secretary Kristi Noem said details were still emerging, but the agency was confirming there were “multiple injuries and fatalities� at the field office. Noem said the motive remained unclear, but noted there has been an uptick in targeting of ICE agents.

ICE and Homeland Security didn’t immediately provide additional details.

A July 4 attack at a injured a police officer, who was shot in the neck. Attackers dressed in black military-style clothing opened fire outside the Prairieland Detention Center in Alvarado, southwest of Dallas, federal prosecutors said. At least 11 people have been charged in connection with the attack.

A man with an assault rifle at federal agents as they were leaving a U.S. Border Patrol facility in McAllen on July 7. The man, identified as Ryan Louis Mosqueda, injured a police officer who responded to the scene before authorities shot and killed him. Police later found other weaponry, ammunition and backpacks inside his car.

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Associated Press reporters Sarah Brumfield in Cockeysville, Maryland, and Jeff Martin, in Atlanta, contributed to this story.