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North Carolina Gov. Roy Cooper said supplies were being airlifted to that part of the state. Buncombe County officials said Interstate 26 between Asheville and South Carolina had reopened, but most other routes into the city were impassible.

Among those rescued from rising waters was nurse Janetta Barfield, whose car was swamped on Friday morning as she left an overnight shift at Asheville’s Mission Hospital. She said she watched a car in front of her drive through standing water and thought it was safe to proceed. But her car stalled, and within minutes water had filled her front seat up to her chest. A nearby police officer helped her to safety.

“It was unbelievable how fast that creek got just in like five minutes," Barfield said.

Early Saturday morning, many gas stations were closed because they didn’t have electricity, and the few that were open had hourlong lines wrapped around the block. Where traffic lights were dark, drivers treated the intersections as four-way stops. The hub of tourism and arts, home to about 94,000 people, was unusually still after floodwaters swamped neighborhoods known for drawing visitors including Biltmore Village and the River Arts District, which is home to numerous galleries, shops and breweries.

More than 700,000 customers were without power across North Carolina, including about 100,000 in Buncombe County.

In Asheville, there was no cellular service and no timeline for restoration. Residents were also directed to boil their water. Local officials said they were working on setting up hubs to distribute food and water.

“We have had some loss of life,” County Emergency Services Director Van Taylor Jones told reporters. However, he said they were not ready to report specifics as they were hindered in contacting next of kin by the communications outages. Police Chief Michael Lamb said his department had a list of about 60 people who relatives had not been able to reach and were seeking welfare checks.

As of Saturday night, the governor's office confirmed 10 storm deaths statewide but did not provide a breakdown of where they occurred.

Officials said they tried to prepare for the storm but its magnitude was beyond what they could have imagined.

“It's not that we (were) not prepared, but this is going to another level,” Sheriff Quentin Miller said. “To say this caught us off guard would be an understatement.”

Atlanta resident Francine Cavanaugh said she has been unable to reach her sister, son or friends in the Asheville area.

“My sister checked in with me yesterday morning to find out how I was in Atlanta,” she said on Saturday. “The storm was just hitting her in Asheville, and she said it sounded really scary outside.”

Cavanaugh said her sister told her she was going to head out to check on guests at a vacation cabin, “and that’s the last I heard of her. I’ve been texting everyone that I know with no response. All phone calls go directly to voicemail.”

About 30 miles (48 kilometers) southeast of Asheville in the town of Edneyville, Genevieve Preece was grateful that her family’s home was largely spared and still had water, power and Wi-Fi. Many neighbors were less fortunate.

Preece, who owns a utility contracting firm, opened her home as a place of refuge for people who needed to fill up water jugs or get in contact with worried family members. Her husband spent hours cutting trees to clear roads with neighbors.

“We need help badly, but we are all doing what we can,” Preece said. “It will be months or years to put us back together again.”

In Tennessee, Gov. Bill Lee and other officials toured the northeastern part of the state by helicopter Saturday. He called the scene “heartbreaking.”

“There’s a great deal of damage, a great deal of heartache, a great deal of work to be done,” Lee said.

U.S. Rep. Diana Harshbarger expressed disbelief at the extent of the damage.

“It’s something like we’ve never seen in this part of the state. Who would have thought a hurricane would do this much damage in East Tennessee?”

In Greene County, Tennessee, the threat from a stressed dam had passed by Saturday afternoon. The Tennessee Valley Authority, which had warned residents overnight that the Nolichucky Dam could breach, said a thorough review determined it was “stable and secure.” It was one of several being closely monitored.

Along the Pigeon River, the small Tennessee city of Newport suffered heavy flooding.

Kendale Ball, who opened his Simpl Cafe in June after relocating from Knoxville, said the water reached nearly thigh-high.

“We never anticipated it to be this devastating,” he said of the storm.

They tried to move some equipment ahead of the flooding but left town when an emergency evacuation was ordered.

“I know we lost our walk-in cooler, all the refrigeration. We’ll have to assess some of the other stuff.”

In Unicoi County, where the people were rescued from the hospital, Elin Fisher and her husband had to move their camper three times to stay ahead of rising waters. They also helped to move eight other campers.

“We would move things and go, ‘Oh, we’re 30 feet above the waterline,’ go help somebody else move their thing to that level, and go, ‘Oh. We’ve got to move. Again.’ And it was just really, really rapid,” said Fisher, who along with her husband teaches whitewater standup paddleboarding on the Nolichucky River. In the middle of the final move, officials closed the road.

“All of our belongings and our home is on the other side of the river, and we can’t get to it,” she said.

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This story has been updated to correct the spelling of Simpl Cafe.

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Loller reported from Nashville, and Walker from Newport, Tennessee. Associated Press writer R.J. Rico in Atlanta contributed.